痛风是一种嘌呤代谢紊乱所致的慢性代谢紊乱疾病, 目前临床上治疗痛风的药物常具有一定的毒副作用,长期服用容易诱发肝肾衰竭等疾病。本文以桑黄菌为研究对象,通过液体发酵的方式得到其子实体和培养液,并利用飞行质谱检测了其相对分子质量为 800~850。
Antfi-gout xanthine oxidase inhibitory activity of water extracts from various mushrooms were deter-mined. The highest xanthine oxidase inhibitory activity was 72.9% in the water exract from fruiting body of Agaricusbraillensis and also were high in the extract from fruiting bodies of Pleurotus salmoneostramineus(60.1%), Phellinusbaumi(57.7%),Agaricus bisporus(56.7%) and Hericium erinacenm(53.4%).
桑黄是一种珍贵的食药两用菌,具有调节免疫力、抗肿瘤、抗氧化、降血糖、 抗癌、护肝等多重功效。本文以产自长白山地区的桑黄子实体粉末为原料,采用 高效、无毒、经济的方法提取其主要活性成分,检测其对肿瘤细胞的生长抑制和 促凋亡作用,与此同时,又测定了其降尿酸效果,在细胞和分子水平上揭示了桑 黄抗肿瘤以及降尿酸的作用机理。